Ehlers-Danlos syndrome (EDS) is a rare congenital connective tissue disorder caused by genetic changes. Those affected have an altered structure or function of collagen, which is responsible for the stability of the skin, joints and blood vessels.

Typical characteristics are an unusually high mobility of the joints (hypermobility), overstretchable, often very soft skin and a tendency to bruising or chronic pain. Depending on the subtype, internal organs, vessels or the cardiovascular system may also be affected. The symptoms and severity vary greatly - from mild discomfort to severe health restrictions.

There is currently no cure. Treatments focus on physiotherapy, pain management, joint stabilization and injury prevention.