Angelman syndrome is a rare genetic disorder caused by a mutation in the UBE3A gene on chromosome 15. Typical symptoms include severe developmental delay, lack of or severely limited speech, motor problems and often epilepsy.

Many children with Angelman have a strikingly cheerful mood, smile or laugh frequently and appear very lively. They also experience sleep disturbances, balance problems and sometimes swallowing difficulties.

Those affected need support in many areas of life - be it communication, mobility, care or cognitive support.