West syndrome, also known as infantile spasms, is a rare neurological disorder in infants characterized by sudden muscle twitching (spasms). These usually occur between the ages of 3 and 12 months and are often accompanied by developmental delays and mental retardation. The causes can be brain damage due to genetic factors, metabolic disorders or birth trauma, although the exact cause often remains unclear.

Diagnosis is based on an EEG, which typically shows irregular brain activity. Treatment mainly consists of administering medication such as corticosteroids or antiepileptic drugs to control the seizures. The prognosis depends on the cause and the timing of treatment. Early treatment can improve the development and quality of life of affected children.